Photodynamic therapy: Palliation and endoscopic technique in cholangiocarcinoma

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Photodynamic Therapy for Perihilar Cholangiocarcinoma

Haroon Shahid, MD, Fellow, Division of Gastroenterology and Hepatology David Loren, MD FASGE, Associate Director, Gastrointestinal Endoscopy, Associate Professor of Medicine Sidney Kimmel College of Medicine Thomas Jefferson University Cholangiocarcinoma of the biliary hilum is an uncommon disease but increasing in incidence. Patients affected by this frequently fatal disease often succumb to c...

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Optimal Endoscopic Palliation of Advanced Hilar Cholangiocarcinoma with Metal Stents

Endoscopic biliary stenting is a well-established palliative procedure for treating obstructive jaundice in patients with unresectable hilar cholangiocarcinoma. Plastic tube stents (PS) have been widely used for the procedure, but self-expandable metallic stents (SEMSs) are becoming increasingly popular because of the associated longer patency. However, there are several unanswered questions re...

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Photodynamic Therapy Plus Chemotherapy Compared with Photodynamic Therapy Alone in Hilar Nonresectable Cholangiocarcinoma

BACKGROUND/AIMS Standard treatments are not available for hilar nonresectable cholangiocarcinoma (NCC). It is unknown whether combination therapy of photodynamic therapy (PDT) plus systemic chemotherapy is superior to PDT alone. METHODS We retrospectively reviewed 68 patients with hilar NCC treated with either PDT plus chemotherapy (PTD-C) or PDT monotherapy (PDT-M). The primary endpoint was ...

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Photodynamic Therapy in Unresectable Cholangiocarcinoma: Not for the Uncommitted

BACKGROUND/AIMS Photodynamic therapy (PDT) in unresectable cholangiocarcinoma has been associated with improved survival. We report a single tertiary care center experience over the past 6 years. METHODS Fifty-five patients with unresectable cholangiocarcinoma received PDT between 2004 and 2010. Plastic stents were placed after PDT to prevent cholangitis. RESULTS Twenty-seven patients (49%)...

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Palliation of oesophageal cancer--endoscopic intubation and laser therapy.

Oesophageal carcinoma, accounting for approximately 10 deaths per 100,000 people annually, is a major health problem in the United Kingdom.' With many patients presenting with disseminated disease, either manifest or occult, curative treatment is applicable to only a small minority. For the majority of patients palliative relief of dysphagia is the goal of treatment. Clinicians have an ever inc...

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ژورنال

عنوان ژورنال: World Journal of Gastrointestinal Endoscopy

سال: 2010

ISSN: 1948-5190

DOI: 10.4253/wjge.v2.i11.357